PTEN p.T319* Reference Standard
CBP10759
詢 價
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| Introduction | |
| Format | Genomic DNA |
| Description |
PTEN p.T319* 是一個在PTEN基因中發(fā)生的無義突變，導(dǎo)致其編碼的蛋白質(zhì)在第319位蘇氨酸（T）處提前終止，產(chǎn)生一個截短且功能喪失的蛋白，從而破壞其關(guān)鍵的抑癌功能，該突變與多種癌癥的發(fā)病風(fēng)險增高相關(guān)。
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| Technical Data | |
| DNA Change | c.955_958del |
| AA Change | p.T319* |
| Mutation type | Deletion |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | NM_000314.8 |
| Cosmic ID | COSM4894 |
| Chr position(GRCh37) | chr10:89720804_89720807 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
