UGT1A1*36 Reference Standard
CBPA0017
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產品描述
產品數據庫
| Introduction | |
| Format | Genomic DNA |
| Description | UGT1A1, UDP-glucuronosyltransferase 1-1, is an enzyme that catalyzes the glucuronidation of substances to soluble metabolites for excretion (PMID: 28520360). Genetic polymorphisms in UGT1A1 may alter the metabolism of chemotherapy drugs such as irinotecan, resulting in severe toxicity. |
| Technical Data | |
| Gene | UGT1A1 |
| AA Change | N/A |
| DNA Change | N/A |
| Chr position (GRCh38) | NC_000002.12_g.233760233_233760234delTA |
| Allelic Frequency | 50% |
| Zygosity | Heterozygous |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8°C |
| Expiry | 36 months from the date of manufacture |
